Application of multiphysics models to efficient design of experiments of solute transport across articular cartilage
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- 作者：Behdad Pourana ; b ; b.pouran-2@umcutrecht.nl" class="auth_mail" title="E-mail the corresponding author ; b.pouran@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Vahid Arbabia ; b ; c ; Harrie Weinansa ; b ; d ; Amir A. Zadpoorb
- 关键词：Articular cartilage ; Iodixanol bath ; Bath stirring ; Stagnant layer ; Micro-CT ; Neutral solute diffusion ; Biphasic-solute finite element model
- 刊名：Computers in Biology and Medicine
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：78
- 期：Complete
- 页码：91-96
- 全文大小：1412 K
文摘
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Effects of bath size and stirring and stagnant layer on diffusion across cartilage.
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Stirring, bath size and concentration of the stagnant layer as dominant factors.
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Applications in intra-articular drug delivery and design of diffusion experiments.