Lipase-catalyzed synthesis of aliphatic polyesters and properties characterization

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• 作者：Wenhui Liu ; Biqiang Chen ; Fang Wang ; Tianwei Tan  ; ;   ; ^{twtan@mail.buct.edu.cn} ; Li Deng
• 关键词：Lipase ; Polyester ; Candida sp.99-12 ; Polymerization ; Diethyl sebacate ; 1 ; 4-Butanediol
• 刊名：Process Biochemistry
• 出版年：2011
• 出版时间：October 2011
• 年：2011
• 卷：46
• 期：10
• 页码：1993-2000
• 全文大小：443 K

文摘

A novel lipase-catalyzed synthesis of aliphatic polyesters has been achieved successfully by using Candida sp.99-125 with diethyl sebacate and 1,4-butanediol as starting substrates in absence of organic solvents. The lipase from Candida sp.99-125 was employed for the first time to catalyze synthesis of poly(butylene sebacate) and showed high catalytic activity for bulkpolymerization under mild reaction conditions. The eco-friendly processes, without any environmental pollution, avoided both phase separation of the reactants and the use of toxic solvents effectively. The polycondensation reactions were performed in two stages: first stage reaction under atmospheric pressure to convert the monomers to oligomers followed by second stage reaction under vacuum process, with a highest molecular weight of 15,800 obtained in molar ratio of 1:1 at 70 ¡ãC. The corresponding polyesters determined by thermogravimetric analysis (TGA) were much thermally stable up to 300 ¡ãC. Differential scanning calorimetry (DSC) and wide-angle X-ray diffraction (WAXS) analysis demonstrated the polymers had a strong ability to crystallize with the degree of crystallinity up to 66 % .