We describe the sequence of three IncA/C2 plasmids carrying In416-like integrons.
Divergent types of IncA/C2 plasmids spread in different species of Enterobacteriaceae.
pKP-Gr642 from a ST383 Klebsiella pneumoniae is related to type 1 IncA/C2 plasmids.
pEcl-Gr4873 from a ST88 Enterobacter cloacae is related to type 2 IncA/C2 plasmids.
These findings underscore the rapid evolution of IncA/C2 plasmids.