Protocol and methodology of the epidemiological mental health study in Andalusia: PISMA-ep

详细信息    查看全文

• 作者：Jorge A. Cervilla^a ; ^b ; ^{jcervilla@ugr.es} ; Isabel Ruiz^c ; Miguel Rodrí ; guez-Barranco^c ; Margarita Rivera^b ; Inmaculada Ibá ; ñ ; ez-Casas^a ; Esther Molina^d ; Eulalio Valmisa^e ; Jos&eacute ; Carmona-Calvo^f ; Berta Moreno-Kü ; stner^g ; Jos&eacute ; Eduardo Muñ ; oz-Negro^a ; ^b ; Ana Ching-Ló ; pez^a ; Blanca Guti&eacute ; rrez^a
• 关键词：Prevalence ; Cross-setional ; Risk factors ; Mental disorder ; Genetics
• 刊名：Revista de Psiquiatría y Salud Mental (English Edition)
• 出版年：2016
• 出版时间：October-December 2016
• 年：2016
• 卷：9
• 期：4
• 页码：185-194
• 全文大小：659 K
• 卷排序：9

文摘

This is the general methods describing paper of a cross-sectional study that aims to detect the prevalence of major mental disorders in Andalusia (Southern Spain), and their correlates or potential risk factors, using a large representative sample of community-dwelling adults.Materials and methodsThis is a cross-sectional study. We undertook a multistage sampling using different standard stratification levels and aimed to interview 4518 randomly selected participants living in all 8 provinces of the Andalusian region utilising a door-knocking approach. The Spanish version of the MINI International Neuropsychiatric Interview, a valid screening instrument ascertaining ICD-10/DSM-IV compatible mental disorder diagnoses was used as our main diagnostic tool. A large battery of other instruments was used to explore global functionality, medical comorbidity, personality traits, cognitive function and exposure to psychosocial potential risk factors. A saliva sample for DNA extraction was also obtained for a sub-genetic study. The interviews were administered and completed by fully trained interviewers, despite most tools used are compatible with lay interviewer use.ResultsA total of 3892 (70.8%) of 5496 initially attempted households had to be substituted for equivalent ones due to either no response (37.7%) or not fulfilling the required participant quota (33%). Thence, out of 5496 eligible participants finally approached, 4507 (83.7%) agreed to take part in the study, completed the interview and were finally included in the study (n = 4507) and 4286 (78%) participants also agreed and consented to provide a saliva sample for DNA study. On the other hand, 989 (16.3%) approached potential participants refused to take part in the study.DiscussionThis is the largest mental health epidemiological study developed in the region of Spain (Andalusia). The response rates and representativeness of the sample obtained are fairly high. The method is particularly comprehensive for this sort of studies and includes both, personality and cognitive assessments, as well as a large array of bio-psycho-social risk measures.