Short-Term Intraocular Pressure Trends Following Intravitreal Pegaptanib (Macugen) Injection

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• 作者：Seenu M. Hariprasad ; Gaurav K. Shah and Kevin J. Blinder
• 刊名：American Journal of Ophthalmology
• 出版年：2006
• 出版时间：January 2006
• 年：2006
• 卷：141
• 期：1
• 页码：200-201
• 全文大小：63 K

文摘

Purpose

To report the changes and trends in intraocular pressures (IOP) following intravitreal injection of Pegaptanib (Macugen) for the treatment of exudative age-related macular degeneration.

Design

Retrospective chart review.

Methods

Review of 79 patients who underwent 122 consecutive Pegaptanib injections. Analysis of the short-term effect of Pegaptanib injections on IOP was performed.

Results

Baseline mean IOP was 15.73 ± 3.41 mm Hg (mean ± standard deviation) with a range of 9 to 27 mm Hg. Postinjection mean IOP was 24.47 ± 6.29 mm Hg with a range of 8 to 36 mm Hg. Mean IOP change from baseline to roughly 30 minutes after Pegaptanib injection was 8.74 ± 7.23 mm Hg. At the 5- to 7-day follow-up visit, IOP had normalized.

Conclusions

Pegaptanib injection in this limited series seems to be safe from an IOP standpoint in the short-term. IOP monitoring postinjection may not be necessary.