Saccharomyces boulardii probiotic-associated fungemia: questioning the safety of this preventive probiotic's use

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• 作者：Isabella W. Martin^a ; ¹ ; Rita Tonner^b ; ¹ ; Julie Trivedi^b ; Heather Miller^a ; Richard Lee^c ; Xinglun Liang^d ; Leo Rotello^e ; Elena Isenbergh^e ; Jennifer Anderson^e ; Trish Perl^f ; ^{tperl@jhmi.edu} ; Sean X. Zhang^a ; ^c ; ^{szhang28@jhmi.edu}
• 关键词：Saccharomyces boulardii ; Probiotic ; Fungemia ; Fungal infection ; Strain typing
• 刊名：Diagnostic Microbiology and Infectious Disease
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：87
• 期：3
• 页码：286-288
• 全文大小：307 K
• 卷排序：87

文摘

Documenting a fungemia case in an immunocompetent patient after administration of probiotic. Concluding the Saccharomyces yeast causing the patient bloodstream infection was indeed from the probiotic capsule. Demonstrating the usefulness and feasibility of the two commercial-available strain-typing methods: DivsersiLab and MALDI-TOF MS. Questioning the safety of this preventative biotherapy in clinical use.