• 作者：Yves Boirie ; Christelle Guillet ; Noë ; l Cano ; Sté ; phane Walr
• 关键词：Muscle ; Sarcopenia ; Dietary protein ; Protein metabolism ; Nutrition ; Hormones ; Exercise
• 刊名：Nutrition clinique et metabolisme
• 出版年：2009
• 出版时间：June 2009
• 年：2009
• 卷：23
• 期：2
• 页码：72-75
• 全文大小：153 K

Control of muscle mass and function is dependent on biochemical processes for synthesis and protein degradation. Dynamic imbalance of these pathways necessarily causes a gain or loss of muscle. These pathways are also regulated by nutrients, hormones or exercise. Thus, it is of interest to understand their effects and their involvement in physiological and pathological conditions such as aging or chronic diseases. Daily metabolic changes induced by food intake can help fight against muscle loss. New strategies to limit sarcopenia are precisely based on the nutritional characteristics of dietary protein, including feeding pattern and the timing of protein ingestion. Essential amino acids are also interesting to reach these objectives. Finally, multimodal therapeutic approaches to limit muscle loss may combine adequate protein intake, physical exercise, hormonal therapy or selective drugs.