Higher Protein but Not Energy Intake Is Associated With a Lower Prevalence of Frailty Among Community-Dwelling Older Adults in the French Three-City Cohort

详细信息    查看全文

• 作者：Berna Rahi ; PhD^a ; ^b ; ^{Berna.rahi@isped.u-bordeaux2.fr" class="auth_mail" title="E-mail the corresponding author} ; Zoé ; Colombet ; Msc^b ; Magali Gonzalez-Colaç ; o Harmand ; MD^a ; ^b ; Jean-Franç ; ois Dartigues ; MD ; PhD^a ; ^b ; Yves Boirie ; MD ; PhD^c ; ^d ; ^e ; Luc Letenneur ; PhD^a ; ^b ; Catherine Feart ; PhD^a ; ^b
• 关键词：Higher protein intake ; optimal energy intake ; frailty ; older adults
• 刊名：Journal of the American Medical Directors Association
• 出版年：2016
• 出版时间：1 July 2016
• 年：2016
• 卷：17
• 期：7
• 页码：672.e7-672.e11
• 全文大小：250 K

文摘

The hypothesis that increasing protein and energy intakes may confer protection against frailty has been suggested, although few studies have examined these associations, especially regarding current protein energy recommendations in the older population.

Aim

To assess the association between frailty and higher protein and energy intakes.

Methods

The present study is a secondary, cross-sectional analysis of the French Three-City cohort. Participants were community-dwelling older adults aged 65 and over. Frailty was defined as a score of 3/5 among the 5 Fried criteria: weight loss, exhaustion, muscle weakness, slowness, and physical activity. Protein intake was set at a daily intake ≥1 g/kg body weight and optimal energy intake defined as a daily intake ≥30 kcal/kg. Logistic regressions were performed while adjusting for several sociodemographic and clinical variables.

Results

The study sample consisted of 1345 participants [mean age (SD) 74.0 (4.9) years], of whom 55 (4.1%) were identified as frail. After adjusting for sociodemographic and clinical variables, higher protein intake was significantly associated with a lower frailty prevalence [odds ratio (OR) = 0.41, 95% confidence interval (CI) = 0.19-0.89; P = .024] whereas no significant association was observed between an optimal energy intake and the presence of frailty (OR = 0.70, 95% CI = 0.32-1.55, P = .38).

Conclusions

A 1 g/kg protein intake was associated with a lower prevalence of frailty in French community-dwelling older subjects. This observation adds to the literature, suggesting increasing the daily protein intake to at least 1 g/kg for older adults aged 65 and more.