Insights into bombesin receptors and ligands: Highlighting recent advances
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- 作者：Irene Ramos-Á ; lvareza ; Paola Morenoa ; Samuel A. Manteya ; Taichi Nakamuraa ; Bernardo Nuche-Berenguera ; Terry W. Moodyb ; David H. Coyc ; Robert T. Jensena ; robertj@bdg10.niddk.nih.gov" class="auth_mail" title="E-mail the corresponding author
- 关键词：βAla ; βalanine ; Bantag-1 ; selective BRS-3 peptide antagonist ; Bn ; bombesin ; BnR ; bombesin receptor ; BRS-3(BB3) ; bombesin receptor subtype 3 ; COOH terminus ; carboxyl terminus ; CCK ; cholecystokinin ; CNS ; central nervous system ; Cpa ; chlorophenylalanine ; DAG ; diacylglycerol ; EC1 ; extracellular domain 1 ; ERK ; extracellular regulated kinase ; EGFR ; epidermal growth factor receptor ; fBB4 ; frog bombesin receptor subtype 4 ; GRP ; gastrin-releasing peptide ; GRPR ; gastrin-releasing peptide receptor (BB2) ; G
- 刊名：Peptides
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：72
- 期：Complete
- 页码：128-144
- 全文大小：3138 K
文摘
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During Prof. Kastin's editorship 5% of articles related to bombesin (Bn) peptides.
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In this Festschrift we review our studies and latest advances by others.
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Advances in pharmacology, cell biology, patho- and normal physiology are reviewed.
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With new ligands, molecular studies their role in many processes is being clarified.
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Particularly important is possible roles in imaging/treating tumors, pruritus, obesity.