Simvastatin enhances VEGF production and ameliorates impaired wound healing in experimental diabetes

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• 作者：Aless ; ra Bitto ; Letteria Minutoli ; Domenica Altavilla ; Francesca Polito ; Tiziana Fiumara ; Herbert Marini ; Mariarosaria Galeano ; Margherita Calò ; Patrizia Lo Cascio ; Michele Bonaiuto ; Alba Miglior
• 关键词：Diabetes ; PECAM-1 ; Simvastatin ; VEGF ; Wound healing
• 刊名：Pharmacological Research
• 出版年：2008
• 出版时间：February 2008
• 年：2008
• 卷：57
• 期：2
• 页码：159-169
• 全文大小：5386 K

文摘

Statins have different effects beyond cholesterol reduction and stimulate angiogenesis. We investigated the effect of simvastatin in diabetes-related healing defects.