Donellanic acids A-C: new cyclopropanic oleanane derivatives from Donella ubanguiensis (Sapotaceae)

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• 作者：Aurelie V.B. Djoumessi^a ; Louis P. Sandjo^a ; ^b ; Johannes C. Liermann^b ; Dieter Schollmeyer^b ; Victor Kuete^c ; Vincent Rincheval^d ; Abegaz M. Berhanu^e ; Samuel O. Yeboah^f ; Pascal Wafo^g ; Bonaventure T. Ngadjui^a ; ^h ; ^{ngadjuibt@yahoo.fr} ; Till Opatz^b ; ^{opatz@uni-mainz.de}
• 关键词：Donella ubanguiensis ; Sapotaceae ; Cyclopropanic triterpenoids ; Biological activities
• 刊名：Tetrahedron
• 出版年：2012
• 出版时间：17 June, 2012
• 年：2012
• 卷：68
• 期：24
• 页码：4621-4627
• 全文大小：691 K

文摘

Three new cyclopropanic oleanane triterpenoids and ten known compounds were obtained from Donella ubanguiensis using chromatographic methods. The structures were established on the basis of mass spectrometric and NMR data and by comparison with values reported in the literature. The structures of the new compounds were confirmed by X-ray crystallography. A part of the isolated compounds was evaluated for cytotoxic and antimicrobial activities.