Lentiviral vector interactions with the host cell

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• 作者：Chiara Borsotti ; Ester Borroni ; Antonia Follenzi ^{antonia.follenzi@med.uniupo.it}
• 刊名：Current Opinion in Virology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：21
• 期：Complete
• 页码：102-108
• 全文大小：390 K
• 卷排序：21

文摘

Two main groups of LVs-inhibiting molecules are described. PPRs recognize LV-derived nucleic acids and activate the host immune response. Other RFs block reverse transcription, nuclear transport and integration. Knowledge of host–vector interactions helps the development of better LVs.