Changes in plasma lecithin: cholesterol acyltransferase activity, HDL₂, HDL₃ amounts and compositions in patients with chronic renal failure after different times of hemodialysis

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• 作者：Mekki ; Khedidja ; Bouchenak ; Malika ; Lamri ; Myriem ; Remaoun ; Mustapha ; Belleville ; Jacques
• 关键词：Chronic renal failure ; Hemodialysis duration ; LCAT ; HDL₂ ; HDL₃
• 刊名：Atherosclerosis
• 出版年：2002
• 出版时间：June, 2002
• 年：2002
• 卷：162
• 期：2
• 页码：409-417
• 全文大小：200 K

文摘

The aim of this study was to investigate the effect of hemodialysis duration on HDL₂ and HDL₃ compositions and lecithin:cholesterol acyltransferase (LCAT) activity in 58 patients on acetate hemodialysis using cuprophane membrane, after different periods of dialysis. Patients were divided into three groups—GI <1 year, GII 1–5 years, GIII 5–13 years of dialysis and were compared with 22 controls. Increase by 34 % of triacylglycerols (TG) was noted in GI and by 36 % in GII versus GI. Hypertriglyceridemia was correlated with hemodialysis duration (HD) (r