Monocopper complex based on N-tripodal ligand immobilized in a Nafion^® film for biomimetic detection of catechols: Application to dopamine

详细信息    查看全文

• 作者：Mina Boulkroune^a ; ^b ; Alizé ; e Lemaire^a ; Aissa Chibani^b ; Florence Geneste^a ; ^{Florence.Geneste@univ-rennes1.fr}
• 关键词：Biomimetic sensor ; Dopamine ; Catechol ; Monocopper complex ; Modified electrode
• 刊名：Electrochimica Acta
• 出版年：2016
• 出版时间：10 December 2016
• 年：2016
• 卷：221
• 期：Complete
• 页码：80-85
• 全文大小：809 K
• 卷排序：221

文摘

A complex based on bis-pyrazolyl N-tripodal ligand known to present a good catalytic activity for the oxidation of 3,5-di-tert-butylcatechol is used to prepare a novel biomimetic sensor for the determination of catechol derivatives. The modified electrode prepared by encapsulation of the complex in a Nafion® film leads to an electrochemical signal 4.4 times higher than with a glassy carbon electrode for dopamine detection in pH 7 medium. After optimization of the conditions used to immobilize the catalyst on the electrode surface, a calibration curve was obtained with linearity in the range of 30–320 μmol L−1 and a detection limit of 8 μmol L−1. The sensor was not affected by ascorbic acid and uric acid in similar concentrations to dopamine and its electrochemical response was stable after 40 determinations. The biomimetic sensor can also be used for the detection of other catechol derivatives.