Immunomodulatory Functions of BTLA and HVEM Govern Induction of Extrathymic Regulatory T Cells and Tolerance by Dendritic Cells
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- 作者：Andrew Jones1 ; Jessica Bourque1 ; Lindsey Kuehm1 ; Adeleye Opejin1 ; Ryan M. Teague1 ; Cindy Gross1 ; Daniel Hawiger1 ; 2 ; dhawiger@slu.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Immunity
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：45
- 期：5
- 页码：1066-1077
- 全文大小：2695 K
文摘
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BTLA+ DCs govern peripheral Treg cell conversion
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Engagement of HVEM increases CD5 expression to promote Foxp3 expression
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BTLAneg DCs fail to induce pTreg cells and tolerance even in the steady state