Evaluation of the anatomical and functional consequences of repetitive mild cervical contusion using a model of spinal concussion
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- 作者：Ying Jin ; Julien Bouyer ; Christopher Haas ; Itzhak Fischer ; ifischer@drexelmed.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Repetitive spinal cord contusion ; Vulnerability ; Behavioral consequences ; Morphological changes ; Spinal cord concussion model
- 刊名：Experimental Neurology
- 出版年：2015
- 出版时间：September 2015
- 年：2015
- 卷：271
- 期：Complete
- 页码：175-188
- 全文大小：2456 K
文摘
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We describe a novel animal model of mild contusion that mimics cervical spinal concussion.
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This injury shows a rapid and full recovery within a week.
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However, repeated injury induces significant and long-term functional deficits and inflammation.
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Our study highlights the vulnerability of the spinal cord to repeated concussions for clinical considerations.