Enzyme-free fluorescent biosensor for the detection of DNA based on core-shell Fe3O4 polydopamine nanoparticles and hybridization chain reaction amplification
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- 作者：Na Li linb@swu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xia Hao ; Bei Hua Kang ; Zhen Xu ; Yan Shi ; Nian Bing Li ; Hong Qun Luo ; luohq@swu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Enzyme free ; DNA ; Fe3O4 polydopamine nanoparticles ; Hybridization chain reaction
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：77
- 期：Complete
- 页码：525-529
- 全文大小：1837 K
文摘
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Enzyme-free DNA detection was developed based on HCR and Fe3O4@PDA NPs.
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Signal amplification was achieved by hybridization chain reaction.
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Fe3O4@PDA NPs were used for homogeneous and rapid HCR products capture efficiently.
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The strategy could distinguish single-base mismatched DNA sequence.