Heritability of calcaneal quantitative ultrasound measures in healthy adults from the Fels Longitudinal Study

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• 作者：Lee ; Miryoung ; Czerwinski ; Stefan A. ; Choh ; Audrey C. ; Towne ; Bradford ; Demerath ; Ellen W. ; et. al.
• 关键词：Osteoporosis ; Quantitative ultrasound ; Heritability ; Genetic correlations ; Family study
• 刊名：Bone
• 出版年：2004
• 出版时间：November, 2004
• 年：2004
• 卷：35
• 期：5
• 页码：1157-1163
• 全文大小：123 K

文摘

Quantitative ultrasound (QUS) measurements of bone have been reported to predict osteoporotic fracture risk in postmenopausal women and older men. Although many studies have examined the heritability of bone mineral density (BMD), few studies have estimated the heritability of calcaneal QUS phenotypes. In the present study, we examined the genetic regulation of calcaneal QUS parameters in individuals from nuclear and extended families.