ALK-rearranged squamous cell lung carcinoma responding to crizotinib: A missing link in the field of non-small cell lung cancer?
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- 作者：Florence Vergnea ; florence.vergne@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; Gilles Qué ; ré ; a ; gilles.quere@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; Sophie Andrieu-Keyb ; sophie.andrieu@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; Renaud Descourta ; renaud.descourt@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; Isabelle Quintin-Roué ; b ; isabelle.quintin-roue@hu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; Matthieu Talagasb ; c ; d ; matthieu.talagas@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; Marc De Braekeleerc ; e ; f ; marc.debraekeleer@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; Pascale Marcorellesb ; c ; d ; pascale.marcorelles@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; Arnaud Uguenb ; c ; f ; arnaud.uguen@chu-brest.fr" class="auth_mail" title="E-mail the corresponding author ; arnaud.uguen@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Lung cancer ; ALK ; Squamous cell carcinoma ; Crizotinib ; Immunohistochemistry
- 刊名：Lung Cancer
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：91
- 期：Complete
- 页码：67-69
- 全文大小：1089 K
文摘
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We report a rare case of ALK-rearranged lung squamous cell carcinoma with response to crizotinib therapy.
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We highlight the challenges in the identification of this rare molecular subtype of lung cancer.
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We point out the overlapping phenotypic criteria between ALK-rearranged squamous cell carcinomas and adenocarcinomas.