文摘
BDNF rapidly stabilizes Lin28a, but not Lin28b, by MAPK-dependent TRBP phosphorylation Lin28a, but not Lin28b, associates with TRBP in the miRNA-generating complex Phospho-TRBP requires Lin28a to mimic neurotrophin-induced dendritic spine growth MAPK-dependent Lin28a induction by trophic cues is conserved in diverse primary cells