- 作者：Brendan Byrne ; Robert Sherwin ; Cheryl Courage ; Alfred Baylor ; Bram Dolcourt ; Jacek R. Brudzewski ; Jeffrey Mosteller ; Robert F. Wilson
- 关键词：H2O2 ; hydrogen peroxide ; hyperbaric oxygen ; gas emboli ; oxygen emboli ; ingestion
- 刊名：Journal of Emergency Medicine
- 出版年：February, 2014
- 年：2014
- 卷：46
- 期：2
- 页码：171-175
- 全文大小：433 K
Background
Hydrogen peroxide is a commonly available product and its ingestion has been demonstrated to produce in聽vivo gas bubbles, which can embolize to devastating effect.Objective
We report two cases of hydrogen peroxide ingestion with resultant gas embolization, one to the portal system and one cerebral embolus, which were successfully treated with hyperbaric oxygen therapy (HBO), and review the literature.
Case Report
Two individuals presented to our center after unintentional ingestion of concentrated hydrogen peroxide solutions. Symptoms were consistent with portal gas emboli (Patient A) and cerebral gas emboli (Patient B), which were demonstrated on imaging. They were successfully treated with HBO and recovered without event.
Conclusions
As demonstrated by both our experience as well as the current literature, HBO has been used to successfully treat gas emboli associated with hydrogen peroxide ingestion. We recommend consideration of HBO in any cases of significant hydrogen peroxide ingestion with a clinical picture compatible with gas emboli.