Ultrasound scan in the detection of fetal malformations at 10 to 14 weeks' gestation

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• 作者：Brizot ; Maria L. ; Pedreira ; Denise A.L. ; Chiba ; Clá ; udia H. ; Reis ; Ná ; dia E.V. ; et. al.
• 刊名：Ultrasound in Medicine and Biology
• 出版年：1997
• 出版时间：1997
• 年：1997
• 卷：23
• 期：Supplement 1
• 页码：S104
• 全文大小：86.0 K

文摘

This study investigate the importance of early ultrasound scan in the detection of fetal malformations. Since October 1995 as part of a study that evaluate screening for fetal chromosomal abnormalities by measurement of nucal translucency thickness (NT) between 10⁺³ to 14⁺⁰ weeks gestation, we also performed a complete fetal anatomical evaluation. This anatomical survey include examine the following fetal structures: head, face, heart, diaphragm, stomach, abdominal wall, bladder, spine and extremities. Ultrasound examination was performed by transabdominal route unless visualisation was poor, in which case vaginal sonography was carried out. 712 fetuses were examined and 356 had EDD up to 15/03/1197 (complete outcome). We detected five fetal structural abnormalities (other than increased fluid collected in the back of the neck - NT): 1 chraniorachisquisis; 1 encephalocele; 1 spine bifida; 1 holoprosencephaly; 1 megacystis. From the 356 completed pregnancies 4 other anomalies were observed: 2 bilateral and 1 unilateral talipes and one cardiac defect. This findings demonstrate that a proper evaluation of the fetal anatomy can identify severe fetal anomalies at an early stage of the pregnancy.