Human brucellosis in France in the 21st century: Results from national surveillance 2004-2013

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• 作者：A. Mailles^a ; ^{alexandra.mailles@santepubliquefrance.fr} ; B. Garin-Bastuji^b ; J.P. Lavigne^c ; ^d ; M. Jay^b ; A. Sotto^c ; ^e ; M. Maurin^f ; I. Pelloux^f ; D. O&rsquo ; Callaghan^d ; V. Mick^b ; V. Vaillant^a ; H. De Valk^a
• 关键词：Brucella ; Epidemiology ; France ; Human ; Zoonosis ; One Health
• 刊名：Médecine et Maladies Infectieuses
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：46
• 期：8
• 页码：411-418
• 全文大小：662 K
• 卷排序：46

文摘

Brucellosis is a bacterial zoonotic disease mainly transmitted to humans by ruminants. In France, brucellosis has disappeared from ruminants herds. Human brucellosis surveillance is performed through mandatory notification and the national reference center.MethodsWe report the results of human brucellosis surveillance from 2004 to 2013 with regards to epidemiological, clinical and microbiological data.ResultsA total of 250 cases were notified, making an annual incidence of 0.3 cases per million inhabitants. Brucella melitensis biovar 3 was the most frequently identified bacterium (79% of isolated strains). In total, 213 (85%) cases had been contaminated abroad in endemic countries. In 2012, an episode of re-emergence of brucellosis in cattle occurred in Haute-Savoie, in the French Alps, and was responsible for 2 human cases.ConclusionBrucellosis has become a disease of travelers in France. However, maintaining a stringent epidemiological surveillance is necessary to be able to early detect any local re-emergence in humans or animals. The multidisciplinary surveillance was implemented in France years ago and is a successful example of the One Health Concept.