Cytotoxic, genotoxic and mutagenic evaluation of surface waters from a coal exploration region

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• 作者：Cynthia Silva Porta^a ; Dé ; bora Lemes dos Santos^a ; Hé ; lio Vieira Bernardes^a ; Bruno Corrê ; a Bellagamba^a ; Anaí ; Duarte^b ; Johnny Ferraz Dias^b ; Fernanda Rabaioli da Silva^c ; Mauricio Lehmann^a ; Juliana da Silva^a ; Rafael Rodrigues Dihl^a ; ^{rafael.rodrigues@ulbra.br}
• 关键词：Coal mining ; Chromosomal instability ; DNA damage ; Drosophila melanogaster ; V79 ; HepG2
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：April 2017
• 年：2017
• 卷：172
• 期：Complete
• 页码：440-448
• 全文大小：520 K
• 卷排序：172

文摘

Toxicity of surface waters impacted by coal exploration was investigated in vivo and in vitro. Water samples inhibited cell proliferation. Water samples increased frequencies of V79 cell death, apoptosis, and necrosis. No genotoxic and mutagenic activities were observed.