Developmental exposure to progestins causes male bias and precocious puberty in zebrafish (Danio rerio)
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- 作者：Johan Svenssona ; johan.svensson@ebc.uu.se" class="auth_mail" title="E-mail the corresponding author ; Arshi Mustafab ; Jerker Fickc ; Monika Schmitzb ; Bjö ; rn Brunströ ; ma
- 关键词：Progestins ; Levonorgestrel ; Progesterone ; Zebrafish ; Sex differentiation ; Puberty
- 刊名：Aquatic Toxicology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：177
- 期：Complete
- 页码：316-323
- 全文大小：2329 K
文摘
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Zebrafish larvae were exposed to levonorgestrel or progesterone during sexual development.
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Levonorgestrel caused all-male populations to develop.
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Both levonorgestrel and progesterone caused precocious puberty in male fish.
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Results confirm that levonorgestrel is an androgenic contaminant of environmental concern.