Systemic inflammation on postnatal days 21 and 28 and indicators of brain dysfunction 2 years later among children born before the 28th week of gestation
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- 作者：Alan Levitona ; alan.leviton@childrens.harvard.edu" class="auth_mail" title="E-mail the corresponding author ; Elizabeth N. Allreda ; Raina N. Fichorovab ; Karl C.K. Kubanc ; T. Michael O'Shead ; Olaf Dammanne ; f ; for the ELGAN study investigators
- 关键词：ELGAN ; extremely low gestational age newborn ; NICU ; Neonatal Intensive Care Unit ; BSID-II ; Bayley Scales of Infant Development &mdash ; Second Edition ; MDI ; mental development index of the BSID-II ; PDI ; psychomotor development index of the BSID-II ; CRP ; C-Reactive Protein ; SAA ; Serum Amyloid A ; MPO ; Myeloperoxidase ; IL-1β ; Interleukin-1 β ; IL-6 ; Interleukin-6 ; IL-6R ; Interleukin-6 Receptor ; TNF-α ; Tumor Necrosis Factor-α ; TNF-R2 ; Tumor Necrosis Factor Receptor-2 ; IL-8 ; Interleukin-8 (CXCL8) ; RANT
- 刊名：Early Human Development
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：93
- 期：Complete
- 页码：25-32
- 全文大小：314 K
文摘
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Extremely low gestational age newborns (ELGANs) can have systemic inflammation during the third and fourth postnatal weeks
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ELGANs who have systemic inflammation during the 3rd and 4th weeks appear to be at increased risk of early ventriculomegaly
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ELGANs who have systemic inflammation during the 3rd and 4th weeks appear to be at increased risk of microcephaly at 2 yrs
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ELGANs with systemic inflammation during the 3rd and 4th weeks appear to be at increased risk of low mental scores at 2 yrs