An approach to heterobifunctional poly(ethyleneglycol) bioconjugates

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• 作者：Jane Li ; Curtis F. Crasto ; James S. Weinberg ; Mansoor Amiji ; Dinesh Shenoy ; Srinivas Sridhar ; Glenn J. Bubley and Graham B. Jones
• 刊名：Bioorganic and Medicinal Chemistry Letters
• 出版年：2005
• 出版时间：2005
• 年：2005
• 卷：15
• 期：24
• 页码：5558-5561
• 全文大小：115 K

文摘

A family of differentially substituted poly(ethyleneglycol) building blocks has been assembled from commercially available material. Their utility is demonstrated by formation of amino acid conjugates, image contrast agents, gold nanoparticles, and functional antibody conjugates. Application in the cellular trafficking of antitumoral agent conjugates is expected.