A porcine model of early atrial fibrillation using a custom-built, radio transmission-controlled pacemaker
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- 作者：Michael Schwarzl ; MD ; PhDa ; Alessio Alogna ; MDb ; David Zweiker ; MDc ; Jochen Verderber ; MDc ; Stefan Huber ; MDd ; Martin Manninger ; MDc ; Daniel Scherr ; MDc ; Gudrun Antoons ; PhDc ; Burkert M. Pieske ; MDb ; Heiner Post ; MDb ; 1 ; heiner.post@charite.de" class="auth_mail" title="E-mail the corresponding author ; Andreas Lueger ; MDe ; 1
- 关键词：Atrial fibrillation ; Atrial remodeling ; Rapid atrial pacing ; Porcine ; DOCA ; Arterial hypertension
- 刊名：Journal of Electrocardiology
- 出版年：2016
- 出版时间：March-April 2016
- 年：2016
- 卷：49
- 期：2
- 页码：124-131
- 全文大小：718 K
文摘
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We present a pig model of early atrial fibrillation using a custom-built pacemaker.
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The spontaneous atrial rhythm was interrogated telemetrically in conscious animals.
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We found atrial structural remodeling and increased stability of atrial fibrillation.
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Evidence of left ventricular dysfunction was not present.
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Experimental arterial hypertension accelerated atrial remodeling.