Hid arbitrates collective cell death in the Drosophila wing
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- 作者：Gianella Garcia-Hughesa ; Nichole Linkb ; Anwesha B. Ghosha ; John M. Abramsa ; John.Abrams@utsouthwestern.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Apoptosis ; Collective cell death ; Eclosion ; Development ; Hormone
- 刊名：Mechanisms of Development
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：138
- 期：part_P3
- 页码：349-355
- 全文大小：1164 K
文摘
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Formation of the Drosophila wing is a model for synchronized collective cell death.
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Clonal analyses show that collective cell does not require cell–cell contact.
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Transcriptional loading of hid defines a pivotal switch anticipating collective PCD.
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The Bursicon hormone-receptor axis elicits collective cell death.