Imaging Transcriptional Regulation of Eukaryotic mRNA Genes: Advances and Outlook
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文摘
Cell imaging provides a new approach to study transcriptional regulation in vivo. TFs, transcription sites, or single mRNAs are the imaging targets. Transcription bursting occurs at many eukaryotic mRNA genes and is regulated. Distal enhancers regulate transcription by modulating bursting kinetics. Molecular insights remain to be discovered by developing transcription imaging.

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