Highly sensitive determination of promazine in pharmaceutical and biological samples using a ZnO nanoparticle-modified ionic liquid carbon paste electrode

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• 作者：Vahid Arabali^a ; Mahmoud Ebrahimi^a ; ^{ebrachem2007@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Hassan Karimi-Maleh^b ; ^{h.karimi.maleh@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Promazine ; ZnO nanoparticle ; Ionic liquid ; Modified electrode
• 刊名：Chinese Chemical Letters
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：27
• 期：5
• 页码：779-782
• 全文大小：719 K

文摘

In this work we describe the first report for the determination of promazine using a nanostructure-modified ionic liquid carbon paste electrode in aqueous solutions. To achieve this goal, a novel modified carbon paste electrode using ZnO nanoparticles and 1-methyl-3-butylimidazolium bromide as a binder (ZnO/NPs/ILs/CPE) was fabricated. The oxidation peak potential of promazine at the surface of the ZnO/NPs/ILs/CPE appeared at 685 mV, which was about 65 mV lower than the oxidation potential at the surface of CPE under similar conditions. Also, the peak current was increased to about 4.0 times higher at the surface of ZnO/NPs/ILs/CPE compared to that of CPE. The linear response range and detection limit were found to be 0.08–450 and 0.04 μmol/L, respectively. The modified electrode was successfully used for the determination of promazine in real samples with satisfactory results.