Discovery of a ring-opened derivative of 3-n-butylphthalide bearing NO/H2S-donating moieties as a potential anti-ischemic stroke agent
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ng class="boldFont">8dng> displayed a better anti-platelet activity than NBP, NO-NBP or H2S-NBP.

ng class="boldFont">8dng> produced moderate levels of NO and H2S.

ng class="boldFont">8dng> possessed more protective effects than NBP on MCAO injury.

ng class="boldFont">8dng> enhanced the levels of SOD, GSH and GSH-Px.

30">ng class="boldFont">8dng> diminished the level of MDA.

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