Diagnostic criteria for and clinical review of melanonychia in Korean patients

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• 作者：Hyunju Jin ; MD^a ; Jeong-Min Kim ; MD^a ; Gun-Wook Kim ; MD^a ; Margaret Song ; MD^a ; Hoon-Soo Kim ; MD^a ; Hyun-Chang Ko ; MD^a ; Byung-Soo Kim ; MD ; PhD^a ; ^b ; Moon-Bum Kim ; MD ; PhD^a ; ^b ; ^{drkmp@hanmail.net" class="auth_mail" title="E-mail the corresponding author}
• 关键词：algorithm ; Korea ; melanonychia ; nail pigmentation ; subungual hemorrhage ; ungual melanoma
• 刊名：Journal of the American Academy of Dermatology
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：74
• 期：6
• 页码：1121-1127
• 全文大小：883 K

文摘

Melanonychia may be the presenting sign of ungual melanoma. However, there are insufficient basic clinical data for melanonychia in Korean patients.

Objective

We sought to identify basic clinical data and devise a classification algorithm for melanonychia.

Methods

In all, 275 patients with melanonychia who visited our clinic from January 2002 to August 2014 were included in this study. We reviewed medical records, clinical and dermoscopic photographs, and histopathologic findings and we assessed demographics (eg, age); medical (eg, systemic diseases), family, and trauma (eg, nail biting) history; and physical findings (eg, affected number and site).

Results

The 5 most common causes of melanonychia in Korean patients were subungual hemorrhage (29.1%), nail matrix nevus (21.8%), trauma-induced pigmentation (14.5%), nail apparatus lentigo (11.6%), and ethnic-type nail pigmentation (8.0%). Melanoma was diagnosed in 6.2% of patients. Ethnic-type nail pigmentation was commonly identified.

Limitations

This is a retrospective study from a single center.

Conclusion

We propose a revised diagnostic algorithm for melanonychia to assist in the evaluation of this condition.