Altered functional connectivity in the default mode network is associated with cognitive impairment and brain anatomical changes in Parkinson's disease

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• 作者：Olaia Lucas-Jimé ; nez^a ; Natalia Ojeda^a ; Javier Peñ ; a^a ; Marí ; a Dí ; ez-Cirarda^a ; Alberto Cabrera-Zubizarreta^b ; Juan Carlos Gó ; mez-Esteban^c ; Marí ; a Á ; ngeles Gó ; mez-Beldarrain^d ; Naroa Ibarretxe-Bilbao^a ; ^{naroa.ibarretxe@deusto.es}
• 关键词：Parkinson's disease ; Default mode network ; Functional connectivity ; Gray matter ; Diffusion-weighted imaging ; Cognitive impairment
• 刊名：Parkinsonism & Related Disorders
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：33
• 期：Complete
• 页码：58-64
• 全文大小：1031 K
• 卷排序：33

文摘

Default mode network (DMN) functional connectivity disruption is present in PD. DMN disruption is related to gray and white matter abnormalities in PD. DMN alteration is related to memory and visual cognitive impairment in PD.