Sensory active piperine analogues from Macropiper excelsum and their effects on intestinal nutrient uptake in Caco-2 cells

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• 作者：Katja Obst^a ; ^{katja.obst@symrise.com} ; Barbara Lieder^b ; Katharina V. Reichelt^a ; Michael Backes^a ; Susanne Paetz^a ; Katrin Geiß ; ler^a ; Gerhard Krammer^a ; Veronika Somoza^b ; Jakob P. Ley^a ; Karl-Heinz Engel^c
• 关键词：Macropiper excelsum ; Piperaceae ; Kawakawa ; Caco-2 ; Glucose uptake ; Fatty acid uptake ; Lignans ; Piperine analogues ; Fatty acid alkamides
• 刊名：Phytochemistry
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：135
• 期：Complete
• 页码：181-190
• 全文大小：961 K
• 卷排序：135

文摘

25 compounds of Macropiper excelsum were identified; of which 14 of them were newly found in this species. Piperine and pellitorine were the most important sensory active compounds causing chemesthetic effects. Some piperine analogues changed intestinal nutrient uptake in Caco-2 cells.