The diagnostic value of circulating cell free DNA quantification in non-small cell lung cancer: A systematic review with meta-analysis
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- 作者：Tao Jianga ; 1 ; Changyun Zhaib ; 1 ; Chunxia Sua ; Shengxiang Rena ; harry_ren@126.com" class="auth_mail" title="E-mail the corresponding author ; Caicun Zhoua ; caicunzhou_dr@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Circulating cell free DNA ; Non-small-cell lung cancer ; Diagnosis ; Meta-analysis
- 刊名：Lung Cancer
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：100
- 期：Complete
- 页码：63-70
- 全文大小：2240 K
文摘
CfDNA could differentiate primary lung cancer from healthy individuals with a high sensitivity and specificity.
Sensitivity could not be improved according to the grouping factors.
Specificity was near to 90% when we unified the sample condition, detection method and reference gene.
Combination of cfDNA quantification with other tumor markers would be the future directions.