The role of cord blood BDNF in infant cognitive impairment induced by low-level prenatal manganese exposure: LW birth cohort, China
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- 作者：Xiaodan Yua ; Limei Chenb ; 1 ; Caifeng Wangb ; Xin Yanga ; Yu Gaob ; Ying Tiana ; b ; tianmiejp@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Prenatal exposure ; Mn ; BDNF ; Children's neurobehavioral development ; Epidemiology
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：163
- 期：Complete
- 页码：446-451
- 全文大小：438 K
文摘
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Prenatal Mn exposure was associated with poor neurodevelopment in children at 1 year of age.
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There was a negative correlation between cord serum Mn and BDNF levels.
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Lower BDNF level was correlated with poor neurodevelopment in children at 1 year of age.
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BDNF plays an important role in cognitive impairment induced by prenatal Mn exposure.