Genetic analysis of MC1R variants in Chinese Han patients with sporadic Parkinson’s disease
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- 作者：Sihan Hea ; b ; Ting Tana ; Zhi Songb ; Lamei Yuana ; Xiong Denga ; Bin Nic ; Yong Chenc ; chenyong0008@sina.com" class="auth_mail" title="E-mail the corresponding author ; Hao Denga ; b ; hdeng008@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：PD ; Parkinson&rsquo ; s disease ; MM ; malignant melanoma ; MC1R ; the melanocortin 1 receptor gene ; GPCR ; G-protein-coupled receptor ; MCRs ; melanocortin receptors ; α-MSH ; α-melanocyte stimulating hormone ; cAMP ; the cyclic AMP ; VPS35 ; the vacuolar protein sorting 35 gene ; FBXO48 ; the F-box only protein 48 gene ; EIF4G1 ; the eukaryotic translation initiation factor 4-gamma 1 gene ; S100B ; the S100 calcium binding protein B gene ; RAB39B ; the RAB39B ; member RAS oncogene family gene ; TCEANC2 ; the transcript
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：12 January 2016
- 年：2016
- 卷：611
- 期：Complete
- 页码：101-105
- 全文大小：507 K
文摘
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We evaluated the association between MC1R variants and sporadic Parkinson’s disease.
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512 Chinese Han patients with sporadic Parkinson’s disease were genotyped.
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Rs3212366, rs33932559, and rs34090186 are not related to Chinese Parkinson’s disease.