Adhesion of Candida biofilm cells to human epithelial cells and polystyrene after treatment with silver nanoparticles
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- 作者：Douglas Roberto Monteiro ; Melyssa Negri ; S贸nia Silva ; Luiz Fern ; o Gorup ; Emerson Rodrigues de Camargo ; Ros谩rio Oliveira ; Debora Barros Barbosa ; Mariana Henriques
- 关键词：Candida ; Epithelial cells ; Polystyrene ; Silver nanoparticles ; Yeast adhesion
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：1 February, 2014
- 年：2014
- 卷：114
- 期：Complete
- 页码：410-412
- 全文大小：425 K
文摘
This study investigated the adhesion to human epithelial cells and polystyrene surface of viable yeasts recovered from Candida biofilms treated with silver nanoparticles (SN). Biofilm resuspended Candida cells were added to HeLa cells or to empty wells of microtiter plates and the adhesion was verified using crystal violet staining. The adhesion of Candida cells was significantly reduced, mainly when biofilms were pretreated with 54 渭g/mL SN. These new findings allow to conclude that SN may induce changes in viable yeasts, which can decrease the dissemination of Candida infections, mainly in susceptible patients.