Development of a high-yield reassortant influenza vaccine virus derived from the A/Anhui/1/2013 (H7N9) strain
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- 作者：Kazuya Nakamura ; Masayuki Shirakura ; Yasushi Suzuki ; Tadasuke Naito1 ; Seiichiro Fujisaki ; Masato Tashiro ; Eri Nobusawa ; nobusawa@nih.go.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：CVV ; candidate vaccine virus ; HA ; hemagglutinin ; MDCK cells ; Madin-Darby canine kidney cells
- 刊名：Vaccine
- 出版年：2016
- 出版时间：12 January 2016
- 年：2016
- 卷：34
- 期：3
- 页码：328-333
- 全文大小：647 K
文摘
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We have developed a 6:2 reassortant vaccine virus for avian influenza A (H7N9).
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The original virus stock, A/Anhui/1/2013 (H7N9), was a quasi-species.
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A125T of NIIDRG-10.1 HA might enhance the growth ability of the virus.