Congenital intestinal anomalies, neonatal short bowel syndrome, and prenatal/neonatal counseling

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• 作者：Germana Casaccia ; Aless ; ro Trucchi ; Ioannis Spirydakis ; Claudio Giorl ; ino ; Lucia Aite ; Irma Capolupo ; Onofrio Antonio Catalano ; Pietro Bagolan
• 刊名：Journal of Pediatric Surgery
• 出版年：2006
• 出版时间：April 2006
• 年：2006
• 卷：41
• 期：4
• 页码：804-807
• 全文大小：80 K

文摘

Short bowel syndrome (SBS) is a severe malabsorption caused by bowel loss. Congenital intestinal anomalies (CIA) detectable by prenatal ultrasound as jejunoileal atresia, meconium peritonitis, complicated meconium ileus, and fetal volvulus can be responsible for SBS.

Aims

This study aims to investigate either frequency of SBS or the morbidity in CIA population during the first admission.

Material and methods

Records of CIA treated from 1997 to 2003 were reviewed. The prenatal ultrasound findings were correlated with SBS. Student's t and χ² tests were performed to analyze epidemiological data, growth at discharge, sepsis, liver disease, catheter-related complications, motor developmental delay, and hospital stay in CIA with and without SBS.

Results

Forty-four CIA: SBS developed in 43 % , ranging from 83 % in volvulus to 0 % in complicated meconium ileus. Thirty-six prenatal diagnoses: a strong correlation with SBS was observed in isolated dilated bowel (58 % ). In SBS neonates, birth weight, gestational age, and growth at discharge were statistically lower, whereas sepsis, motor delay, and hospital stay were statistically higher.

Conclusions

Many neonates with CIA detectable by prenatal ultrasound develop SBS. Short bowel syndrome presents a significant higher morbidity. The counseling should stress the frequent association between CIA and SBS as well as the significant morbidity in SBS.