High-Sensitivity Troponin T and N-Terminal Pro-Brain Natriuretic Peptide in Prediction of Outcome in Congenital Diaphragmatic Hernia: Results from a Multicenter, Randomized Controlled Trial

详细信息    查看全文

• 作者：Kitty G. Snoek ; MD¹ ; Ulrike S. Kraemer ; MD¹ ; Chantal A. ten Kate ; Bsc¹ ; Anne Greenough ; MD² ; Arno van Heijst ; MD ; PhD³ ; Irma Capolupo ; MD ; PhD⁴ ; Thomas Schaible ; MD ; PhD⁵ ; Joost van Rosmalen ; PhD⁶ ; René ; M. Wijnen ; MD ; PhD¹ ; Irwin K.M. Reiss ; MD ; PhD⁷ ; Dick Tibboel ; MD ; PhD¹
• 关键词：Biomarkers ; pulmonary hypertension
• 刊名：The Journal of Pediatrics
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：173
• 期：Complete
• 页码：245-249.e4
• 全文大小：207 K

文摘

Biomarkers may be helpful in prediction of outcomes of infants with congenital diaphragmatic hernia. The predictive value of high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide was investigated in 128 infants with congenital diaphragmatic hernia. After correction for multiple testing, those biomarkers did not predict severe pulmonary hypertension, death, need of extracorporeal membrane oxygenation, or bronchopulmonary dysplasia.

Trial registration

Netherlands Trial Registry: 1310.