Defective aggregation in cirrhosis is independent of in vivo platelet activation

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• 作者：Laffi ; Giacomo ; Cinotti ; Sandro ; Filimberti ; Ermino ; Ciabattoni ; Giovanni ; Caporale ; Roberto ; et. al.
• 关键词：Cirrhosis ; Flow cytometry ; GMP 140 ; GP 53 ; Platelet aggregation ; Thromboxane ; 11-dehydro-TXB₂ ; 2 ; 3-dinor-TXB₂
• 刊名：Journal of Hepatology
• 出版年：1996
• 出版时间：April, 1996
• 年：1996
• 卷：24
• 期：4
• 页码：436-443
• 全文大小：874 K

文摘

Background/Aims: Platelet function abnormalities contribute to the hemostatic defect in patients with cirrhosis. In this study we evaluated the occurrence of in vivo platelet activation as a possible mechanism of defective platelet aggregation in patients with cirrhosis.