Small-bowel capsule endoscopy with panoramic view: results of the first multicenter, observational study (with videos)

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• 作者：Gian Eugenio Tontini ; MD ; PhD¹ ; ; Felix Wiedbrauck ; MD ; OA² ; Flaminia Cavallaro ; MD ; PhD¹ ; Anastasios Koulaouzidis ; MD ; FEBG ; FRPCE ; FACG³ ; Roberta Marino ; MD⁴ ; Luca Pastorelli ; MD ; PhD¹ ; ⁵ ; Luisa Spina ; MD ; PhD¹ ; Mark E. McAlindon ; BM ; BS ; BMed Sci ; MRCP ; PhD⁶ ; Piera Leoni ; MD⁴ ; Pasquale Vitagliano ; MD⁷ ; Sergio Cadoni ; MD⁸ ; Emanuele Rondonotti ; MD ; PhD⁹ ; Maurizio Vecchi ; MD¹ ; ⁵
• 关键词：CD ; Crohn disease ; DY ; diagnostic yield ; GTT ; gastric transit time ; IQR ; interquartile range ; OGIB ; obscure gastrointestinal bleeding ; SBTT ; small-bowel transit time ; VCE ; video-capsule endoscopy
• 刊名：Gastrointestinal Endoscopy
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：85
• 期：2
• 页码：401-408.e2
• 全文大小：926 K
• 卷排序：85

文摘

The first small-bowel video-capsule endoscopy (VCE) with 360° panoramic view has been developed recently. This new capsule has wire-free technology, 4 high-frame-rate cameras, and a long-lasting battery life. The aim of the present study was to assess the performance and safety profile of the 360° panoramic-view capsule in a large series of patients from a multicenter clinical practice setting.MethodsConsecutive patients undergoing a 360° panoramic-view capsule procedure in 7 European Institutions between January 2011 and November 2015 were included. Both technical (ie, technical failures, completion rate) and clinical (ie, indication, findings, retention rate) data were collected by means of a structured questionnaire. VCE findings were classified according to the likelihood of explaining the reason for referral: P0, low; P1, intermediate; P2, high.ResultsOf the 172 patients (94 men; median age, 68 years; interquartile range, 53-75), 142 underwent VCE for obscure (32 overt, 110 occult) GI bleeding (OGIB), and 28 for suspected (17) or established (2) Crohn's disease (CD). Overall, 560 findings were detected; 252 were classified as P2. The overall diagnostic yield was 40.1%; 42.2% and 30.0% in patients with OGIB and CD, respectively. The rate of complete enteroscopy was 90.2%. All patients but one, who experienced capsule retention (1/172, 0.6%), excreted and retrieved the capsule. VCE failure occurred in 4 of 172 (2.3%) patients because of technical problems.ConclusionsThis multicenter study, conducted in the clinical practice setting and based on a large consecutive series of patients, showed that the diagnostic yield and safety profile of the 360° panoramic-view capsule are similar to those of forward-view VCEs.