Platinum desensitization in patients with carboplatin hypersensitivity: A single-institution retrospective study

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• 作者：Gary Altwerger ; MD ; ^{gary.altwerger@yale.edu} ; Gregory M. Gressel ; MD ; Diana P. English ; MD ; Wendelin K. Nelson ; PharmD ; Nina Carusillo ; PAC ; Dan-Arin Silasi ; MD ; Masoud Azodi ; MD ; Alessandro Santin ; MD ; Peter E. Schwartz ; MD ; Elena S. Ratner ; MD
• 关键词：Carboplatin desensitization ; Gynecologic malignancy ; Allergy to carboplatin ; Hypersensitivity reactions
• 刊名：Gynecologic Oncology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：144
• 期：1
• 页码：77-82
• 全文大小：302 K
• 卷排序：144

文摘

Highlights an effective, safe and short desensitization protocol Allows hypersensitive patients to continue with carboplatin therapy Employs a straightforward home and inpatient premedication regimen Identifies factors that help to risk stratify patients undergoing desensitization Decreases the burden on health care by reducing admissions to the hospital and ICU