MicroRNA-24 induces cisplatin resistance by targeting PTEN in human tongue squamous cell carcinoma
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- 作者：Xiangqian Zhenga ; 1 ; xiangqian_zheng@163.com" class="auth_mail" title="E-mail the corresponding author ; Jiansen Lib ; 1 ; Chen Penga ; 1 ; Jingzhu Zhaoa ; Jiadong Chia ; Xiangrui Mengc ; Xinwei Yuna ; Dapeng Lib ; Yang Yua ; Ming Gaoa ; ; Yigong Lia ;
- 关键词：MicroRNA-24 ; PTEN ; Cisplatin resistance ; Tongue squamous carcinoma
- 刊名：Oral Oncology
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：51
- 期：11
- 页码：998-1003
- 全文大小：1503 K
文摘
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MicroRNA-24 target PTEN.
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miR-24 plays an important role in the cell survival and cisplatin resistance of TSCC.
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miR-24 induces cisplatin resistance primarily through targeting PTEN/Akt pathway.