A rare case of true carcinosarcoma of the breast

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• 作者：Antonello Accurso^a ; Giuseppe Ciancia^b ; Gianni Antonio Della Corte^c ; Paola Reale^c ; Giuseppe Accardo^c ; Carmela Salerno^c ; Daniele Bordoni^d ; Giuseppe Falco^e ; Nicola Rocco^c ; ^{nicolarocco2003@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Carcinosarcoma ; Biphasic metaplastic sarcomatoid carcinoma ; Rare breast tumours
• 刊名：International Journal of Surgery Case Reports
• 出版年：2016
• 出版时间：2016
• 年：2016
• 卷：21
• 期：Complete
• 页码：125-128
• 全文大小：1039 K

文摘

True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08–0.2% of all breast malignancies.

The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transition zone between the two elements.

Case presentation

We present a case of a 49-year-old woman presenting with a 4 cm mass at the level of her left breast upper-outer quadrant with a histologic diagnosis of true carcinosarcoma of the breast.

Discussion

The most appropriate therapeutic regimens for breast carcinosarcoma are still unclear because of the rarity of this condition, but Breast Conserving Treatment (BCT) followed by adjuvant chemotherapy seems to provide a prognosis equalling that of usual Invasive Ductal Carcinoma of the breast.