Role of microRNAs in the regulation of innate immune cells under neuroinflammatory conditions
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- 作者：Ana L Cardoso1 ; 5 ; Joana R Guedes1 ; 2 ; 3 ; 5 ; Maria C Pedroso de Lima1 ; 4 ; mdelima@ci.uc.pt" class="auth_mail" title="E-mail the corresponding author
- 刊名：Current Opinion in Pharmacology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：26
- 期：Complete
- 页码：1-9
- 全文大小：716 K
文摘
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Transcriptome studies suggest miRNAs can be used as microglia phenotype markers.
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MiR-124 regulates the quiescent state of microglia in the brain.
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The immune role of miR-146a and miR-155 depends on the type of brain injury.
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Transcription kinetics of miRNAs/target mRNAs control miRNA immune regulatory role.