Functional basis of associative learning and their relationships with long-term potentiation evoked in the involved neural circuits: Lessons from studies in behaving mammals
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- 作者：Agnè ; s Gruart ; agrumas@upo.es" class="auth_mail" title="E-mail the corresponding author ; Rocí ; o Leal-Campanario ; Juan Carlos Ló ; pez-Ramos ; José ; M. Delgado-Garcí ; a
- 关键词：Classical eyeblink conditioning ; Operant conditioning ; Hippocampus ; Prefrontal cortex ; Mice ; Rabbits ; Long-term potentiation ; Activity-dependent changes in synaptic strength
- 刊名：Neurobiology of Learning and Memory
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：124
- 期：Complete
- 页码：3-18
- 全文大小：5327 K
文摘
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Hippocampal synapses are differentially modified during classical conditioning.
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Hippocampal inputs and intrinsic circuits have specific roles in classical conditioning.
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Prefrontal and striatum synapses are directly modified by operant conditioning.
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The prefrontal cortex controls the release of acquired motor abilities.
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Experimentally evoked LTP occludes classical, but not instrumental, conditioning.