Conventional Dendritic Cells Confer Protection against Mouse Cytomegalovirus Infection via TLR9 and MyD88 Signaling
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- 作者：Franz Puttur1 ; 11 ; Marcela Francozo1 ; 2 ; 11 ; Gü ; lhas Solmaz1 ; Carlos Bueno1 ; 3 ; Marc Lindenberg1 ; Melanie Gohmert1 ; Maxine Swallow1 ; Dejene Tufa4 ; Roland Jacobs4 ; Stefan Lienenklaus5 ; 6 ; Anja A. Kü ; hl7 ; Lisa Borkner8 ; Luka Cicin-Sain8 ; Bernard Holzmann9 ; Hermann Wagner10 ; Luciana Berod1 ; Tim Sparwasser1 ; 12 ; tim.sparwasser@twincore.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：MCMV ; NK cells ; plasmacytoid DC ; conventional DC ; TLR9-MyD88 signaling
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：18 October 2016
- 年：2016
- 卷：17
- 期：4
- 页码：1113-1127
- 全文大小：4157 K
文摘
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Generation of a mouse model to study DC-specific TLR9 function
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cDC uses TLR9- and MyD88-dependent mechanisms to promote MCMV immunity
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cDC-derived cytokines control independent NK cell effector responses against MCMV